Process optimization for making stable emulsions using accelerated dispersion analysis by multisample analytical centrifugation

S. Kuchler¹, C. Schneider², D. Lerche¹, T. Sobisch¹, LabPlus International (2006) September: 14-18.

Abstract: A common goal in the formation of stable emulsions during a homegenisation process is to obtain the smallest possible particle size distribution of the dispersed phase. The choice of emulsification process and process parameters (e.g. type of homogenizer, temperature, energy input, time, and homogenization cycles) used to achieve this goal depneds on the precise characteristics of the desired emulsion. This article describes the use of a versatile and proven processor for the optimal production of emulsions and shows how a multisample analytical centrifugation system can be used to characterise the emulsions.

Key words: Emulsion stability • Emulsion particle size distribution • homogenization • Microfluidizer • Process parameters • Emulsification • analytical centrifugation • process optimization

¹ LUM GmbH, Rudower Chaussee 29, 12489 Berlin, Germany; ² Microfluidics, Edisonstr. 15, 68623 Lamperthein, Germany.

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